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CD99 Recombinant Protein

Product Specifications

Background

CD99 antigen is also known as MIC2, single-chain type-1 glycoprotein, HBA71, MIC2X, MIC2Y, MSK5X, 12E7, which belongs to the CD99 family. CD99 / MIC2 is expressed on all leukocytes but highest on thymocytes. Involved in T-cell adhesion processes and in spontaneous rosette formation with erythrocytes. CD99 / MIC2 plays a role in a late step of leukocyte extravasation helping leukocytes to overcome the endothelial basement membrane. CD99 acts at the same site as, but independently of PECAM1. There is also experimental evidence that it binds to cyclophilin A.

CAS Number

9000-83-3

NCBI Gene ID

4267

Swiss Prot

P14209

Accession Number

AAH02584

Tag

C-Fc Tag

Type

Recombinant Proteins

Source

HEK293 cells

Field of Research

Signal Transduction

Purity

>92% as determined by SDS-PAGE.

Buffer

50 mM tris, 100 mM glycine, pH7.5

Shipping Conditions

Room Temp

Storage Conditions

Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

36.2 kDa

Applications Notes

This recombinant protein can be used for WB. For research use only.

NCBI Official Name

CD99 molecule

NCBI Organism

Homo sapiens

Background Reference 01

Gelin C., et al., 1989, EMBO J. 8:3253-3259.

Background Reference 02

Aussel C., et al., 1993, Biochemistry 32 (38) : 10096–101.

Background Reference 03

Dworzak MN., et al., 1994, Blood 83 (2) : 415–25.

Background Reference 04

Bernard G., et al., 1997, Journal of immunology (Baltimore, Md. : 1950) 158 (6) : 2543–50.

Other Product Names

CD99, HBA71, MIC2, MIC2X, MIC2Y, MSK5X, 12E7

Tested Applications

WB

Species

Human

Physical Properties

Lyophilized

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