CD48 / SLAMF2 Recombinant Protein
Product Specifications
Background
CD48 antigen is also known as Signaling lymphocytic activation molecule 2, SLAM family member 2 (SLAMF2), Leukocyte antigen MEM-102, BCM1 surface antigen, B-lymphocyte activation marker BLAST-1. CD48 is a 65 kDa GPI-linked protein which belongs to the CD2 subfamily of immunoglobulin superfamily molecules. CD48 antigen contains two Ig-like C2-type (immunoglobulin-like) domains and two Ig-like V-type (immunoglobulin-like) domain. CD48 interacts with CD244 in an heterophilic manner. CD48 is ligand for CD2. CD48 might facilitate interaction between activated lymphocytes. CD48 is probably involved in regulating T-cell activation.
NCBI Gene ID
962
Swiss Prot
P09326
Accession Number
NP_001769.2
Tag
Mouse IgG Fc Tag
Type
Recombinant Proteins
Source
HEK293 cells
Field of Research
Apoptosis, Cancer
Purity
>95% as determined by SDS-PAGE.
Buffer
50 mM Tris, 100 mM Glycine, 150 mM NaCl, pH7.5
Shipping Conditions
Room Temp
Storage Conditions
Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=11-464
Calculated Molecular Weight
49.2 kDa
Applications Notes
This protein carries a mouse IgG2a Fc tag at the C-terminus. The protein has a calculated MW of 49.2 kDa. The protein migrates as 64-70 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
NCBI Official Name
CD48 molecule
NCBI Organism
Homo sapiens
Background Reference 01
Korinek V., et al., 1991, Immunogenetics 33:108-112.
Background Reference 02
Wollscheid B., et al., 2009, Nat. Biotechnol. 27:378-386.
Other Product Names
CD48, BCM1, SLAMF2, BLAST, BLAST1, MEM-102, TCT.1, BCM-1, SLAMF-2, BLAST-1
Tested Applications
ELISA, WB
Species
Human
Physical Properties
Lyophilized
CAS Number
9000-83-3
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