CD48 / SLAMF2 Recombinant Protein

Product Specifications

Background

CD48 antigen is also known as Signaling lymphocytic activation molecule 2, SLAM family member 2 (SLAMF2), Leukocyte antigen MEM-102, BCM1 surface antigen, B-lymphocyte activation marker BLAST-1. CD48 is a 65 kDa GPI-linked protein which belongs to the CD2 subfamily of immunoglobulin superfamily molecules. CD48 antigen contains two Ig-like C2-type (immunoglobulin-like) domains and two Ig-like V-type (immunoglobulin-like) domain. CD48 interacts with CD244 in an heterophilic manner. CD48 is ligand for CD2. CD48 might facilitate interaction between activated lymphocytes. CD48 is probably involved in regulating T-cell activation.

CAS Number

9000-83-3

NCBI Gene ID

962

Swiss Prot

P09326

Accession Number

NP_001769.2

Tag

Mouse IgG Fc Tag

Type

Recombinant Proteins

Source

HEK293 cells

Field of Research

Apoptosis, Cancer

Purity

>95% as determined by SDS-PAGE.

Buffer

50 mM Tris, 100 mM Glycine, 150 mM NaCl, pH7.5

Shipping Conditions

Room Temp

Storage Conditions

Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

49.2 kDa

Applications Notes

This protein carries a mouse IgG2a Fc tag at the C-terminus. The protein has a calculated MW of 49.2 kDa. The protein migrates as 64-70 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.