CD44 Recombinant Protein
Product Specifications
Background
CD44 is a cell-surface receptor for hyaluronic acid and also interacts with other ligands, such as osteopontin, collagens, and matrix metalloproteinases. A large number of CD44 isoforms can be generated by the insertion of different combinations of at least nine exons. Increased CD44 antigen is associated with relapses in non-small cell lung cancers. Furthermore, an increasing quantity of evidence suggests that CD44 has various functions related to inflammatory disease. CD44 deficiency induces severe liver injury. CD44-hyaluronate mediates in lymphocyte T and monocyte adhesion to the endothelium, stimulates proinflammatory cytokine release from macrophages and participates in dedifferentiation phenotype of smooth muscle cells from contractile state to synthetic one.
NCBI Gene ID
960
Swiss Prot
P16070
Accession Number
P16070
Tag
C-Fc tag
Type
Recombinant Proteins
Source
Human Cells
Field of Research
Signal Transduction, Stem Cell, Other
Buffer
Lyophilized from a 0.2 um filtered solution of 20mM PB,150mM NaCl, pH7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.
Shipping Conditions
Room Temp
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=91-888
Calculated Molecular Weight
49.2 kD
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
CD44 molecule (Indian blood group)
NCBI Organism
Homo sapiens
Other Product Names
CD44 Antigen, CDw44, Epican, Extracellular Matrix Receptor III, ECMR-III, GP90 Lymphocyte Homing/Adhesion Receptor, HUTCH-I, Heparan Sulfate Proteoglycan, Hermes Antigen, Hyaluronate Receptor, Phagocytic Glycoprotein 1, PGP-1, Phagocytic Glycoprotein I, PGP-I, CD44, LHR, MDU2, MDU3, MIC4
Species
Human
Physical Properties
Lyophilized
CAS Number
9000-83-3
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