TCblR Recombinant Protein
Product Specifications
Background
CD320 antigen is also known as 8D6 antigen, FDC-signaling molecule 8D6, Transcobalamin receptor and 8D6A. It is a single-pass type I membrane protein and containing two LDL-receptor class A domains. CD320 has been recently discovered and reported as a follicular dendritic cell (FDC) protein. CD320 can augments the proliferation of plasma cells precursors generated by IL-10. CD320 also founctions a receptor for the cellular uptake of transcobalamin bound cobalamin. Defects in CD320 are the cause of methylmalonic aciduria type TCblR (MMATC) which is a metabolic disorder.
NCBI Gene ID
51293
Swiss Prot
Q9NPF0
Accession Number
Q9NPF0
Tag
C-Fc tag
Type
Recombinant Proteins
Source
Human Cells
Field of Research
Cell Cycle, Immunology
Buffer
Lyophilized from a 0.2 um filtered solution of 20mM Tris,150mM NaCl, pH 8.0. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.
Shipping Conditions
Room Temp
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=91-933
Calculated Molecular Weight
47.3 kD
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
CD320 molecule
NCBI Organism
Homo sapiens
Other Product Names
CD320 antigen, 8D6 antigen, FDC-signaling molecule 8D6, FDC-SM-8D6, Transcobalamin receptor, TCblR, CD320, 8D6A
Species
Human
Protein ID
78070603
Physical Properties
Lyophilized
CAS Number
9000-83-3
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