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CD30 Ligand / TNFSF8 Recombinant Protein

Product Specifications

Background

CD30 ligand (CD30L) and CD30 are interacting cellsurface glycoproteins that are members of the tumour necrosis factor (TNF) and tumour necrosis factor receptor (TNFR) superfamilies. In humans, CD30L is expressed at high levels on activated T cells. There is conflicting evidence with regard to cell surface expression of CD30L on primary human B cells. An initial report of constitutive CD30L expression on peripheral blood B cells33 has not been substantiated.

CAS Number

9000-83-3

NCBI Gene ID

8741

Swiss Prot

O75888

Accession Number

NP_003799.1

Tag

His Tag

Type

Recombinant Proteins

Source

HEK293 cells

Field of Research

Immunology

Purity

>90% as determined by SDS-PAGE.

Buffer

PBS, pH7.4

Shipping Conditions

Room Temp

Storage Conditions

Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

21.5 kDa

Applications Notes

This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 21.5 kDa. The protein migrates as 30-40 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

NCBI Official Name

TNF superfamily member 13

NCBI Organism

Homo sapiens

Background Reference 01

Marín ND., et al. 2017, Tuberculosis (Edinb) ., 102, 8-15.

Background Reference 02

Kennedy MK., et al. 2006, Immunology., 118 (2), 143-52.

Background Reference 03

Horie R., et al. 1998, Semin Immunol., 10 (6), 457-70.

Other Product Names

CD30-L, CD153, TNFSF8, CD30L, CD30LG, CD153 antigen, CD30 antigen ligand, CD30 Ligand

Tested Applications

ELISA, WB

Species

Human

Physical Properties

Lyophilized

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