CD24 Recombinant Protein
Product Specifications
Background
CD24 may have a pivotal role in cell differentiation of different cell types. Signaling could be triggered by the binding of a lectin-like ligand to the CD24 carbohydrates, and transduced by the release of second messengers derived from the GPI-anchor. Modulates B-cell activation responses. Promotes AG-dependent proliferation of B-cells, and prevents their terminal differentiation into antibody-forming cells. In association with SIGLEC10 may be involved in the selective suppression of the immune response to danger-associated molecular patterns (DAMPs) such as HMGB1, HSP70 and HSP90. Plays a role in the control of autoimmunity.
NCBI Gene ID
100133941
Swiss Prot
P25063
Accession Number
NP_001278666.1
Tag
Mouse IgG Fc Tag
Type
Recombinant Proteins
Source
HEK293 cells
Field of Research
Signal Transduction, Stem Cell, Other
Purity
>90% as determined by SDS-PAGE.
Buffer
50 mM Tris, 100 mM Glycine, 150 mM NaCl, pH7.5
Shipping Conditions
Room Temp
Storage Conditions
Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=11-271
Calculated Molecular Weight
30.0 kDa
Applications Notes
This protein carries a mouse IgG2a Fc tag at the C-terminus. The protein has a calculated MW of 30.0 kDa. The protein migrates as 40-55 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
NCBI Official Name
CD24molecule
NCBI Organism
Homo sapiens
Background Reference 01
Suzuki T1, et al. 2001. J Immunol. 166 (9) :5567-77.
Background Reference 02
Chen Z, et al. 2017. Biomed Pharmacother. 90:427-436.
Background Reference 03
Eyvazi S, et al. 2018. Curr Cancer Drug Targets. 18 (4) :328-336.
Other Product Names
CD24, CD24A
Tested Applications
ELISA, WB
Species
Human
Physical Properties
Lyophilized
CAS Number
9000-83-3
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
B3FH 50 µL
pAB-bee-FH. FLAG and His tagging of secreted and transmembrane proteins in baculovirus system.
Ask
View Details 
