CD229 / SLAMF3 Recombinant Protein
Product Specifications
Background
CD229, also known as Ly9 and SLAMF3, is a 120 kDa type I transmembrane glycoprotein in the SLAM subgroup of the CD2 family. Signaling lymphocyte activation molecule (SLAM) family receptors are critically involved in modulating innate and adaptive immune responses. CD229 is expressed on T and B cells, thymocytes, and more weakly on NK cells. Homophilic binding between CD229 molecules is mediated by the N-terminal Ig-like domain.
CAS Number
9000-83-3
NCBI Gene ID
4063
Swiss Prot
Q9HBG7
Accession Number
NP_002339.2
Tag
His Tag
Type
Recombinant Proteins
Source
HEK293 cells
Field of Research
Immunology, Signal Transduction
Purity
>90% as determined by SDS-PAGE.
Buffer
PBS, pH7.4
Shipping Conditions
Room Temp
Storage Conditions
Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.
Calculated Molecular Weight
46.7 kDa
Applications Notes
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 46.7 kDa. The protein migrates as 60-66 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
NCBI Official Name
Lymphocyte antigen 9
NCBI Organism
Homo sapiens
Background Reference 01
Bhat R., et al. 2006, J Leukoc Biol., 79 (3), 417-24.
Background Reference 02
De la Fuente MA., et al. 2001, Blood., 97 (11), 3513-20.
Background Reference 03
Graham DB., et al. 2006, J Immunol., 176 (1), 291-300.
Other Product Names
SLAMF3, LY9, Ly-9, hly9, Ly9
Tested Applications
WB
Species
Human
Physical Properties
Lyophilized
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