CD200 Recombinant Protein
Product Specifications
Background
CD200 is also known as OX-2 membrane glycoprotein (OX-2), is a type-1 membrane glycoprotein, which contains two immunoglobulin domains (1 Ig-like C2-type (immunoglobulin-like) domain and Ig-like V-type (immunoglobulin-like) domain), and thus belongs to the immunoglobulin superfamily. CD200 / OX-2 is widely expressed in multiple cell types. CD200 interacts with a structurally related receptor (CD200R) expressed mainly on myeloid cells and is involved in regulation of macrophage and mast cell function. OX-2 / CD200 and CD200R associate via their respective N-terminal Ig-like domains. CD200 also plays an important role in prevention of graft rejection, autoimmune diseases and spontaneous abortion.
CAS Number
9000-83-3
NCBI Gene ID
4345
Swiss Prot
P41217
Accession Number
AAH22522
Tag
C-Fc Tag
Type
Recombinant Proteins
Source
HEK293 cells
Field of Research
Immunology
Purity
>95% as determined by SDS-PAGE.
Buffer
50 mM tris, 100 mM glycine, pH7.5
Shipping Conditions
Room Temp
Storage Conditions
Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.
Calculated Molecular Weight
48.6 kDa
Applications Notes
This recombinant protein can be used for WB. For research use only.
NCBI Official Name
CD200 molecule
NCBI Organism
Homo sapiens
Background Reference 01
McCaughan, G.W. et al., 1987, Immunogenetics 25:329-335.
Background Reference 02
Chen, Z. et al., 2006, Mol Immunol. 43 (6) : 579-587.
Background Reference 03
Wright GJ., et al., 2003, J. Immunol. 171 (6) : 3034–46.
Other Product Names
CD200, MOX1, MOX2, MRC, OX-2, My033
Tested Applications
WB
Species
Human
Physical Properties
Lyophilized
Curated Selection
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