CD155 / PVR Recombinant Protein
Product Specifications
Background
CD155 (cluster of differentiation 155) also known as the poliovirus receptor is a protein that is encoded by the PVR gene. CD155 is a Type I transmembrane glycoprotein in the immunoglobulin superfamily. Commonly known as Poliovirus Receptor (PVR) due to its involvement in the cellular poliovirus infection in primates, CD155's normal cellular function is in the establishment of intercellular adherens junctions between epithelial cells. The role of CD155 in the immune system is unclear, though it may be involved in intestinal humoral immune responses. Subsequent data has also suggested that CD155 may also be used to positively select MHC-independent T cells in the thymus.
NCBI Gene ID
52118
Accession Number
NP_081790.1
Tag
Mouse IgG Fc Tag
Type
Recombinant Proteins
Source
HEK293 cells
Field of Research
Infectious Disease, Neuroscience
Purity
>95% as determined by reduced SDS-PAGE.
Buffer
Tris with Glycine, Arginine and NaCl, pH7.5
Shipping Conditions
Room Temp
Storage Conditions
Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=11-539
Calculated Molecular Weight
61.8 kDa
Applications Notes
This protein carries a mouse IgG2a Fc tag at the C-terminus. The protein has a calculated MW of 61.8 kDa. The protein migrates as 35 kDa and 70-100 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
NCBI Official Name
Poliovirus receptor
NCBI Organism
Mus musculus
Background Reference 01
Zhang P., et al., 2008, Proc. Natl. Acad. Sci., 105 (47) : 18284-18289.
Background Reference 02
Maier MK., et al., 2007, European Journal of Immunology, 37 (8) : 2214-2225.
Background Reference 03
He Y., et al., 2000, Proc. Natl. Acad. Sci., 97 (1) : 79-84.
Other Product Names
PVR, FLJ25946, PVS, CD155, TAGE4, HVED, NECL5
Tested Applications
ELISA, WB
Species
Mouse
Physical Properties
Lyophilized
CAS Number
9000-83-3
Curated Selection
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