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TNFRSF7 Recombinant Protein

Product Specifications

Background

CD Antigen CD27 is also known as Tumor necrosis factor receptor superfamily member 7 (TNFRSF7), which belongs to TNF-receptor superfamily. CD27 / TNFRSF7 is found in most T-lymphocytes. CD27 / TNFRSF7 is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-κB and MAPK8/JNK. CD27 has been shown to interact with SIVA1, TRAF2 and TRAF3.

CAS Number

9000-83-3

NCBI Gene ID

939

Swiss Prot

P26842

Accession Number

NP_001233

Tag

C-Fc Tag

Type

Recombinant Proteins

Source

HEK293 cells

Field of Research

Apoptosis, Cancer, Growth Factors, Immunology, Signal Transduction, Stem Cell

Purity

>95% as determined by SDS-PAGE.

Buffer

50 mM tris, 100 mM glycine, pH7.5

Shipping Conditions

Room Temp

Storage Conditions

Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

45.9 kDa

Applications Notes

This recombinant protein can be used for WB. For research use only.

NCBI Official Name

CD27 molecule

NCBI Organism

Homo sapiens

Background Reference 01

Zhang Z., et al., 2004, Protein Sci. 13:2819-2824.

Background Reference 02

Gravestein L.A., et al., 1998, Eur. J. Immunol. 28:2208-2216.

Background Reference 03

Prasad K.V.S., et al., 1997, Proc. Natl. Acad. Sci. U.S.A. 94:6346-6351.

Other Product Names

CD27, TNFRSF7, S152, S152. LPFS2, T14, Tp55

Tested Applications

WB

Species

Human

Physical Properties

Lyophilized

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