TNFRSF7 Recombinant Protein
Product Specifications
Background
CD Antigen CD27 is also known as Tumor necrosis factor receptor superfamily member 7 (TNFRSF7), which belongs to TNF-receptor superfamily. CD27 / TNFRSF7 is found in most T-lymphocytes. CD27 / TNFRSF7 is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-κB and MAPK8/JNK. CD27 has been shown to interact with SIVA1, TRAF2 and TRAF3.
CAS Number
9000-83-3
NCBI Gene ID
939
Swiss Prot
P26842
Accession Number
NP_001233
Tag
C-Fc Tag
Type
Recombinant Proteins
Source
HEK293 cells
Field of Research
Apoptosis, Cancer, Growth Factors, Immunology, Signal Transduction, Stem Cell
Purity
>95% as determined by SDS-PAGE.
Buffer
50 mM tris, 100 mM glycine, pH7.5
Shipping Conditions
Room Temp
Storage Conditions
Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.
Calculated Molecular Weight
45.9 kDa
Applications Notes
This recombinant protein can be used for WB. For research use only.
NCBI Official Name
CD27 molecule
NCBI Organism
Homo sapiens
Background Reference 01
Zhang Z., et al., 2004, Protein Sci. 13:2819-2824.
Background Reference 02
Gravestein L.A., et al., 1998, Eur. J. Immunol. 28:2208-2216.
Background Reference 03
Prasad K.V.S., et al., 1997, Proc. Natl. Acad. Sci. U.S.A. 94:6346-6351.
Other Product Names
CD27, TNFRSF7, S152, S152. LPFS2, T14, Tp55
Tested Applications
WB
Species
Human
Physical Properties
Lyophilized
Curated Selection
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