CEACAM 8 Recombinant Protein
Product Specifications
Background
Carcinoembryonic antigen-related cell adhesion molecule 8 (CEACAM8) is also known as CD66b (Cluster of Differentiation 66b), CD66b, CD67, CGM6, NCA-95, and is one of seven human CEACAM family members within the immunoglobulin superfamily. CEACAM family members are a set of widely expressed proteins involved in several biological functions, including cell adhesion, migration, signal transduction, and the regulation of gene expression. Abnormal overexpression and downregulation of some CEACAMs have been described in tumor cells. In humans, CEACAMs include type I transmembrane proteins (CEACAM1, CEACAM3, and CEACAM4) and GPI-linked molecules (CEACAM5 through CEACAM8) . There is no human CEACAM2. CEACAM8 is a single chain, two Ig-like C2-type (immunoglobulin-like) domains and one Ig-like V-type (immunoglobulin-like) domain. It is an activation marker for human granulocytes.
NCBI Gene ID
1088
Swiss Prot
P31997
Accession Number
NP_001807.2
Tag
His Tag
Type
Recombinant Proteins
Source
HEK293 cells
Field of Research
Innate Immunity
Purity
>95% as determined by SDS-PAGE.
Buffer
PBS, pH7.4
Shipping Conditions
Room Temp
Storage Conditions
Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=96-181
Calculated Molecular Weight
33 kDa
Applications Notes
This recombinant protein can be used for WB. For research use only.
NCBI Official Name
Carcinoembryonic antigen-related cell adhesion molecule 8
NCBI Organism
Homo sapiens
Background Reference 01
Oikawa, S. et al., 2000, Biochem Biophys Res Commun 278 (3) :564-8.
Background Reference 02
Lasa, A. et al., 2008, Ann Hematol 87 (3) :205-11.
Background Reference 03
Ramachandran P, et al., 2006, J. Proteome Res. 5 (6) : 1493–503.
Background Reference 04
Zhao L, et al., 2002, J. Immunol. Methods 270 (1) : 27–35.
Other Product Names
CEACAM8, CD66b, CD67, CGM6, NCA-95
Tested Applications
WB
Species
Human
Physical Properties
Lyophilized
CAS Number
9000-83-3
Curated Selection
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