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CEACAM 1 Recombinant Protein

Product Specifications

Background

Carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1) is also known as Biliary glycoprotein 1 (BGP1), CD66a, which belongs to the immunoglobulin superfamily or CEA family. CEACAM1 /CD66a contains three Ig-like C2-type (immunoglobulin-like) domains and one Ig-like V-type (immunoglobulin-like) domain. CEACAM1 /CD66a was described as an adhesion molecule mediating cell adhesion via both homophilic and heterophilic manners, and was detected on leukocytes, epithelia, and endothelia. Studies have revealed that CEACAM1 / BGP-1 performs actions in multiple cellular processes including tissue differentiation, angiogenesis, apoptosis, metastasis, as well as the modulation of innate and adaptive immune responses.

CAS Number

9000-83-3

NCBI Gene ID

634

Swiss Prot

P13688

Accession Number

AAH14473

Tag

His Tag

Type

Recombinant Proteins

Source

HEK293 cells

Field of Research

Cancer, Immunology

Purity

>92% as determined by SDS-PAGE.

Buffer

PBS, pH7.4

Shipping Conditions

Room Temp

Storage Conditions

Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

44.2 kDa

Applications Notes

This recombinant protein can be used for WB. For research use only.

NCBI Official Name

Carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)

NCBI Organism

Homo sapiens

Background Reference 01

Kuroki M., et al., 1991, Biochem. Biophys. Res. Commun. 176:578-585.

Background Reference 02

Watt S.M., et al., 1994, Blood 84:200-210.

Background Reference 03

Chen R., et al., 2009, J. Proteome Res. 8:651-661.

Background Reference 04

Hoek KS., et al., 2008, Pigment Cell Melanoma Res. 21 (6) : 665–76.

Other Product Names

CEACAM1, CD66a, BGP, BGP1, BGPI

Tested Applications

WB

Species

Human

Physical Properties

Lyophilized

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