PKA RI alpha Recombinant Protein
Product Specifications
Background
CAMP-dependent protein kinase type I-alpha regulatory subunit is an enzyme that in humans is encoded by the PRKAR1A gene. cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase A (PKA), which transduces the signal through phosphorylationof different target proteins. Four different regulatory subunits and three catalytic subunits of PKA have been identified in humans. The protein encoded by this gene is one of the regulatory subunits. This protein was found to be a tissue-specific extinguisher that down-regulates the expression of seven liver genes in hepatoma x fibroblast hybrids.
NCBI Gene ID
5573
Swiss Prot
P10644
Accession Number
P10644
Tag
C-6 His tag
Type
Recombinant Proteins
Source
Human Cells
Buffer
Lyophilized from a 0.2 um filtered solution of 20mM PB,150mM NaCl, pH7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.
Shipping Conditions
Room Temp
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=92-433
Calculated Molecular Weight
44 kD
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
Protein kinase cAMP-dependent type I regulatory subunit alpha
NCBI Organism
Homo sapiens
Other Product Names
Tissue-specific extinguisher 1, TSE1, PRKAR1A
Species
Human
Physical Properties
Lyophilized
CAS Number
9000-83-3
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