CD52 Recombinant Protein
Product Specifications
Background
CAMPATH-1 antigen, also known as cluster of differentiation 52 (CD52), is a glycoprotein that in humans is encoded by the CD52 gene.It is widely expressed on the cell surface of immune cells, such as mature lymphocytes, natural killer cells (NK), eosinophils, neutrophils, monocytes/macrophages, and dendritic cells (DCs) .ligation of cell surface CD52 molecules may offer costimulatory signals for T-cell activation and proliferation.
CAS Number
9000-83-3
NCBI Gene ID
1043
Swiss Prot
P31358
Accession Number
NP_001794.2
Tag
Fc Tag
Type
Recombinant Proteins
Source
HEK293 cells
Field of Research
Chemokines & Cytokines, Immunology, Other
Purity
>95% as determined by SDS-PAGE.
Buffer
Tris with Glycine, Arginine and NaCl, pH7.5
Shipping Conditions
Room Temp
Storage Conditions
Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.
Calculated Molecular Weight
27.9 kDa
Applications Notes
This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 27.9 kDa. The protein migrates as 38-43 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
NCBI Official Name
CD52 molecule
NCBI Organism
Homo sapiens
Background Reference 01
Zhao Y., et al., 2017 , Immunogenetics.
Background Reference 02
Hersh C., et al., 2014, Immunotherapy. 6 (3) :249-59.
Background Reference 03
Zinzani PL., et al., 2012, Leuk Lymphoma. 53 (5) :789-9
Other Product Names
CDW52, HE5, CD52, CAMPATH-1 antigen
Tested Applications
ELISA, WB
Species
Human
Physical Properties
Lyophilized
Curated Selection
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