Calreticulin Recombinant Protein
Product Specifications
Background
Calreticulin is involved in regulation of intracellular Ca2+ homoeostasis and ER Ca2+ capacity. It constitutes together with calnexin and ERp57 the ‘calreticulin/calnexin cycle’ that is responsible for folding and quality control of newly synthesized glycoproteins. Calreticulin has been implicated to play a role in many biological systems, including functions inside and outside the ER, indicating that the protein is a multi-process molecule. Recently, Calreticulin was shown to enhance the merger of macrophages and tumor cells, increasing phagocytosis.
NCBI Gene ID
811
Swiss Prot
Q8BGW1
Accession Number
P27797
Tag
His Tag
Type
Recombinant Proteins
Source
E. coli
Field of Research
Cancer, Immunology, Obesity, Signal Transduction
Concentration
0.3mg/ml
Buffer
0.2um-filtered solution in 55mM TRIS-Cl, pH 8.2, containing 150mM NaCl.
Shipping Conditions
Blue Ice
Storage Conditions
Working aliquots are stable for up to 3 months when stored at -20˚ C.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=90-138
Applications Notes
This recombinant proteins is for research use only.
NCBI Official Name
Calreticulin
NCBI Organism
Homo sapiens
Other Product Names
CRP55, Calregulin, Endoplasmic Reticulum Resident Protein 60, ERp60, grp60
Species
Human
Protein ID
4757900
Physical Properties
Liquid
CAS Number
9000-83-3
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