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BTN3A1 Recombinant Protein

Product Specifications

Background

Butyrophilin subfamily 3 member A1 (BTN3A1) is also known as CD277 and BTF5, which belongs to the immunoglobulin superfamily and contains one B30.2/SPRY domain and two Ig-like V-type (immunoglobulin-like) domains. BTN3A1 plays a role in T-cell activation and in the adaptive immune response. Also, BTN3A1 regulates the proliferation of activated T-cells and the release of cytokines and IFNG by activated T-cells. Furthermore, BTN3A1 mediates the response of T-cells toward infected and transformed cells that are characterized by high levels of phosphorylated metabolites, such as isopentenyl pyrophosphate.

CAS Number

9000-83-3

NCBI Gene ID

+011118-12-31T23:00:00.000Z

Swiss Prot

O00481

Accession Number

AAI21801

Tag

Fc Tag

Type

Recombinant Proteins

Source

HEK293 cells

Field of Research

Other

Buffer

Tris with Glycine, Arginine and NaCl, pH7.5

Shipping Conditions

Room Temp

Storage Conditions

Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

50.8 kDa

Applications Notes

This recombinant protein can be used for WB. For research use only.

NCBI Official Name

Butyrophilin, subfamily 3, member A1

NCBI Organism

Homo sapiens

Background Reference 01

Yamashiro H., et al., 2010, J. Leukoc. Biol. 88:757-767.

Background Reference 02

Messal N., et al., 2011, Eur. J. Immunol. 41:3443-3454.

Background Reference 03

Harly C., et al., 2012, Blood 120:2269-2279.

Other Product Names

BTN3A1, CD277, BTF5

Tested Applications

WB

Species

Human

Physical Properties

Lyophilized

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