BCAS2 Recombinant Protein
Product Specifications
Background
Breast Carcinoma-Amplified Sequence 2 (BCAS2) is a member of the SPF27 family. BCAS2 is a nuclear protein and widely expressed in many rtissues. BCAS2 is identified as being overexpressed in various breast cancer cell lines. BCAS2 is a component of the spliceosome, taking part in the removal of introns from mRNA precursors. BCAS2 interacts with estrogen receptor alpha and beta, thyroid hormone receptor beta, peroxisome proliferator-activated receptor gamma. BCAS2 functions as an ER co-activator and is capable of enhancing ER-mediated transcription.
CAS Number
9000-83-3
NCBI Gene ID
10286
Swiss Prot
O75934
Accession Number
O75934
Tag
C-6 His, N-T7 tag
Type
Recombinant Proteins
Source
E. coli
Field of Research
Apoptosis, Cancer, Cell Cycle
Buffer
Lyophilized from a 0.2 um filtered solution of 20mM TrisHCl, 200mM NaCl, 2mM DTT, pH 8.0. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.
Shipping Conditions
Room Temp
Calculated Molecular Weight
28.58 kD
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
Breast carcinoma amplified sequence 2
NCBI Organism
Homo sapiens
Other Product Names
Pre-mRNA-Splicing Factor SPF27, Breast Carcinoma-Amplified Sequence 2, DNA Amplified in Mammary Carcinoma 1 Protein, Spliceosome-Associated Protein SPF 27, BCAS2, DAM1
Species
Human
Physical Properties
Lyophilized
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