BDNF Recombinant Protein

Product Specifications

Background

Brain-Derived Neurotrophic Factor (BDNF) is a member of the neurotrophin family. Along with other structurally related neurotrophic factors NGF, NT-3 and NT-4, BDNF binds with high affinity to the TrkB kinase receptor. It also binds with the LNGFR (for low-affinity nerve growth factor receptor, also known as p75) . BDNF promotes the survival, growth and differentiation of neurons. It serves as a major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. BDNF expression is altered in neurodegenerative disorders such as Parkinson's and Alzheimer's disease.

CAS Number

9000-83-3

NCBI Gene ID

627

Swiss Prot

P23560

Accession Number

P23560

Tag

Tag Free

Type

Recombinant Proteins

Source

E. coli

Field of Research

Growth Factors, Neuroscience, Obesity, Signal Transduction, Stem Cell

Buffer

Lyophilized from a 0.2 um filtered solution of 20mM PB, 250mM NaCl, pH 7.2. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.