BST2 Recombinant Protein
Product Specifications
Background
Bone Marrow Stromal Antigen 2 (BST2) is a single-pass type II membrane protein that belongs to the tetherin family. BST2 is predominantly expressed in the liver, lung, heart and placenta. BST2 is involved in the sorting of secreted proteins. BST2 is a human cellular protein which inhibits retrovirus infection by preventing the diffusion of virus particles after budding from infected cells. BST2 is initially discovered as an inhibitor to HIV-1 infection in the absence of Vpu, it has also been shown to inhibit the release of other viruses such as retroviruses, filoviruses, arenaviruses, and herpes viruses. BST2 may play a role in B-cell activation in rheumatoid arthritis.
NCBI Gene ID
684
Swiss Prot
Q10589
Accession Number
Q10589
Tag
C-6 His tag
Type
Recombinant Proteins
Source
Human Cells
Field of Research
Cancer, Infectious Disease
Buffer
Lyophilized from a 0.2 um filtered solution of 20mM PB,150mM NaCl, pH7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.
Shipping Conditions
Room Temp
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=91-773
Calculated Molecular Weight
13.67 kD
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
Bone marrow stromal cell antigen 2
NCBI Organism
Homo sapiens
Other Product Names
Bone Marrow Stromal Antigen 2, BST-2, HM1.24 Antigen, Tetherin, CD317, BST2, CD137
Species
Human
Protein ID
767904139
Physical Properties
Lyophilized
CAS Number
9000-83-3
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