Bisphosphoglycerate Mutase Recombinant Protein

Product Specifications

Background

Bisphosphoglycerate Mutase (BPGM) is a member of the Phosphoglycerate Mutase family and BPG-Dependent PGAM subfamily. BPGM is a multifunctional enzyme. BPGM catalyzes 2,3-DPG synthesis via its synthetase activity, and 2,3-DPG degradation via its phosphatase activity. It also has phosphoglycerate phosphomutase activity. BPGM plays a major role in regulating hemoglobin oxygen affinity by controlling the levels of 2,3-bisphosphoglycerate (2,3-BPG) . Deficiency of BPGM increases the affinity of cells for oxygen and result in hemolytic anemia.

CAS Number

9000-83-3

NCBI Gene ID

669

Swiss Prot

P07738

Accession Number

P07738

Tag

C-6 His tag

Type

Recombinant Proteins

Source

E. coli

Field of Research

Obesity, Signal Transduction

Buffer

Supplied as a 0.2 um filtered solution of 20mM Tris, 1mM DTT, pH 8.0 . It is not recommended to reconstitute to a concentration less than 100 ug/ml.

Shipping Conditions

Dry Ice

Calculated Molecular Weight

31 kD

Applications Notes

This recombinant protein can be used for biological assays. For research use only.

NCBI Official Name

Bisphosphoglycerate mutase

NCBI Organism

Homo sapiens

Other Product Names

Bisphosphoglycerate Mutase, BPGM, 2, 3-Bisphosphoglycerate Mutase Erythrocyte, 3-Bisphosphoglycerate Synthase, 3-Diphosphoglycerate Mutase, DPGM, BPG-Dependent PGAM