Bisphosphoglycerate Mutase Recombinant Protein
Product Specifications
Background
Bisphosphoglycerate Mutase (BPGM) is a member of the Phosphoglycerate Mutase family and BPG-Dependent PGAM subfamily. BPGM is a multifunctional enzyme. BPGM catalyzes 2,3-DPG synthesis via its synthetase activity, and 2,3-DPG degradation via its phosphatase activity. It also has phosphoglycerate phosphomutase activity. BPGM plays a major role in regulating hemoglobin oxygen affinity by controlling the levels of 2,3-bisphosphoglycerate (2,3-BPG) . Deficiency of BPGM increases the affinity of cells for oxygen and result in hemolytic anemia.
NCBI Gene ID
669
Swiss Prot
P07738
Accession Number
P07738
Tag
C-6 His tag
Type
Recombinant Proteins
Source
E. coli
Field of Research
Obesity, Signal Transduction
Buffer
Supplied as a 0.2 um filtered solution of 20mM Tris, 1mM DTT, pH 8.0 . It is not recommended to reconstitute to a concentration less than 100 ug/ml.
Shipping Conditions
Dry Ice
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=92-092
Calculated Molecular Weight
31 kD
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
Bisphosphoglycerate mutase
NCBI Organism
Homo sapiens
Other Product Names
Bisphosphoglycerate Mutase, BPGM, 2, 3-Bisphosphoglycerate Mutase Erythrocyte, 3-Bisphosphoglycerate Synthase, 3-Diphosphoglycerate Mutase, DPGM, BPG-Dependent PGAM
Species
Human
Protein ID
767983919
Physical Properties
Liquid
CAS Number
9000-83-3
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