CD72 Recombinant Protein
Product Specifications
Background
B-Cell Differentiation Antigen CD72 (CD72) is a single-pass type II membrane protein. CD72 exists as a disulfide-linked homodimer and contains one C-type lectin domain. CD72 is expressed on B lineage cells, NK cells, monocytes, dendritic cells, and mast cells. CD72 is a ligand for CD5. CD72 associates with CD5, interacts with PTPN6/SHP-1 and plays a role in B-cell proliferation and differentiation. CD72 associates with CD79A in the B cell antigen receptor (BCR) complex following antigen stimulation and dampens BCR signaling through interactions with the phosphatase SHP-1.
NCBI Gene ID
971
Swiss Prot
P21854
Accession Number
P21854
Tag
N-Trx, 6 His tag
Type
Recombinant Proteins
Source
E. coli
Field of Research
Immunology, Signal Transduction
Buffer
Lyophilized from a 0.2 um filtered solution of 20mM PB,150mM NaCl, pH7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.
Shipping Conditions
Room Temp
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=92-070
Calculated Molecular Weight
30.6 kD
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
CD72 molecule
NCBI Organism
Homo sapiens
Other Product Names
B-Cell Differentiation Antigen CD72, Lyb-2, CD72, Lyb‑2
Species
Human
Protein ID
578877726
Physical Properties
Lyophilized
CAS Number
9000-83-3
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