BIRC5 Recombinant Protein
Product Specifications
Background
Baculoviral IAP Repeat-Containing Protein 5 (BIRC5) belongs to the IAP family. BIRC5 exists as a homodimer in the apo state and as a monomer in the CPC-bound state. BIRC5 contains one BIR repeat and is expressed only in fetal kidney and liver, and to lesser extent, lung and brain. BIRC5 functions as a multitasking protein that has dual roles in promoting cell proliferation and preventing apoptosis. BIRC5 is also a component of a chromosome passage protein complex (CPC), which is essential for chromosome alignment and segregation during mitosis and cytokinesis. BIRC5 acts as an important regulator of the localization of this complex.
NCBI Gene ID
332
Swiss Prot
O15392
Accession Number
O15392
Tag
Tag Free
Type
Recombinant Proteins
Source
E. coli
Field of Research
Apoptosis, Cancer, Growth Factors, Neuroscience
Buffer
Lyophilized from a 0.2 um filtered solution of 20mM Tris, 0.1M NaCl, pH 7.5. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.
Shipping Conditions
Room Temp
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=92-047
Calculated Molecular Weight
20.4 kD
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
Baculoviral IAP repeat containing 5
NCBI Organism
Homo sapiens
Other Product Names
Baculoviral IAP Repeat-Containing Protein 5, Apoptosis Inhibitor 4, Apoptosis Inhibitor Survivin, BIRC5, API4, IAP4
Species
Human
Physical Properties
Lyophilized
CAS Number
9000-83-3
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