BTLA Recombinant Protein
Product Specifications
Background
B- and T-lymphocyte attenuator (BTLA) is also known as B- and T-lymphocyte-associated protein, CD antigen CD272. BTLA contains one Ig-like V-type (immunoglobulin-like) domain. As a lymphocyte inhibitory receptor, BTLA / CD272 inhibits lymphocytes during immune response. BTLA / CD272 can interact with tyrosine phosphatases PTPN6/SHP-1 and PTPN11/SHP-2, and interact with TNFRSF14/HVEM.
CAS Number
9000-83-3
NCBI Gene ID
151888
Swiss Prot
Q7Z6A9
Accession Number
NP_001078826.1
Tag
C-Fc Tag
Type
Recombinant Proteins
Source
HEK293 cells
Field of Research
Immunology, Innate Immunity, Obesity
Purity
>90% as determined by SDS-PAGE.
Buffer
Tris with Glycine, Arginine and NaCl, pH7.5
Shipping Conditions
Room Temp
Storage Conditions
Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.
Calculated Molecular Weight
38.7 kDa
Applications Notes
This recombinant protein can be used for WB. For research use only.
NCBI Official Name
B and T lymphocyte associated
NCBI Organism
Homo sapiens
Background Reference 01
Watanabe N., et al., 2003, Nat. Immunol. 4:670-679.
Background Reference 02
Gavrieli M., et al., 2003, Biochem. Biophys. Res. Commun. 312:1236-1243.
Background Reference 03
Sedy J.R., et al., 2005, Nat. Immunol. 6:90-98.
Other Product Names
BTLA, CD272
Tested Applications
WB
Species
Human
Physical Properties
Lyophilized
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