BAX Recombinant Protein
Product Specifications
Background
Apoptosis Regulator BAX (BAX) belongs to the Bcl-2 family. BAX exists as a homodimer and is expressed in a wide variety of tissues. The Bax gene encodes different isoforms including Bax alpha (21 kDa) and Bax beta (24 kDa) . Although both isoforms contain BH1, BH2 and BH3 domains, Bax beta has a unique carboxyl terminus and does not contain a hydrophobic transmembrane domain. BAX accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. BAX also promotes activation of CASP3, and thereby apoptosis.
CAS Number
9000-83-3
NCBI Gene ID
581
Swiss Prot
Q07812
Accession Number
Q07812
Tag
N, C-6 His tag
Type
Recombinant Proteins
Source
E. coli
Field of Research
Apoptosis, Autophagy, Cancer, Homeostasis, Other
Buffer
Lyophilized from a 0.2 um filtered solution of 20mM PB,150mM NaCl, pH7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.
Shipping Conditions
Room Temp
Calculated Molecular Weight
22.1 kD
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
BCL2-associated X protein
NCBI Organism
Homo sapiens
Other Product Names
Apoptosis Regulator BAX, Bcl-2-Like Protein 4, Bcl2-L-4, BAX, BCL2L4
Species
Human
Protein ID
767904139
Physical Properties
Lyophilized
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