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ApolipoRecombinant Protein A-II / APOA2 Recombinant Protein

Product Specifications

Background

Apolipoprotein A-II (APO-A2) stabilize HDL (high density lipoprotein) structure by its association with lipids, and affect the HDL metabolism. It is produced by the liver and is involved in cholesteryl ester formation and cholesterol transport from tissues to the liver. Recent studies have established the interaction between APOA2 -256T>C polymorphism and dietary saturated fatty acids intake in relation to obesity on healthy individuals. Significant interaction between APOA2-saturated fatty acids intake and body mass index (BMI) . The result of this study confirmed the interaction between APOA2 -256T>C polymorphism and SFAs intake with BMI in type 2 diabetic patients.

CAS Number

9000-83-3

NCBI Gene ID

336

Swiss Prot

P02652

Accession Number

NP_001634.1

Tag

His Tag

Type

Recombinant Proteins

Source

E. coli

Purity

>90% as determined by SDS-PAGE.

Buffer

PBS, pH7.4

Shipping Conditions

Room Temp

Storage Conditions

Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

11.3 kDa

Applications Notes

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 11.3 kDa. The protein migrates as 11 kDa and 13 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

NCBI Official Name

Apolipoprotein A2

NCBI Organism

Homo sapiens

Background Reference 01

Kobayashi T, et al. 2018. Biochem Biophys Res Commun. 497 (3) :903-907.

Background Reference 02

Basiri MG, et al. 2015. Genes Nutr. 10 (3) :464.

Background Reference 03

Ma C, et al. 2015. Biomed Res Int. 2015:481621.

Other Product Names

Apolipoprotein A-II, APOA2, Apo-AII, ApoA-II, Apolipoprotein A2

Tested Applications

WB

Species

Human

Physical Properties

Lyophilized

Frequently Asked Questions

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