Serpin A8 Recombinant Protein

Product Specifications

Background

Angiotensinogen is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia. Genetic variations in Angiotensinogen are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in the encoding gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease.

CAS Number

9000-83-3

NCBI Gene ID

183

Swiss Prot

P01019

Accession Number

P01019

Tag

C-6 His tag

Type

Recombinant Proteins

Source

Human Cells

Field of Research

Cancer, Neuroscience, Obesity, Signal Transduction

Buffer

Supplied as a 0.2 um filtered solution of 20mM PB,150mM NaCl, pH7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml.

Shipping Conditions

Dry Ice

Calculated Molecular Weight

51.7 kD

Applications Notes

This recombinant protein can be used for biological assays. For research use only.

NCBI Official Name

Angiotensinogen

NCBI Organism

Homo sapiens

Other Product Names

Angiotensinogen, also called Serpin A8, AGT and SERPINA8, is expressed by the liver and secreted in plasma. Angiotensinogen is a member of the serpin family.