ACE-2 Recombinant Protein
Product Specifications
Background
Angiotensin-Converting Enzyme 2 (ACE-2) is an integral membrane protein and a zinc metalloprotease of the ACE family, the ACE family includes somatic and germinal ACE. ACE-2 cleaves angiotensins I and II as a carboxypeptidase, ACE-2 converts angiotensin I to angiotensin 1-9, and angiotensin II to angiotensin 1-7. ACE-2 is also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. ACE-2 can be high expressed in testis, kidney and heart, in colon, small intestine and ovary at moderate levels. Captopril and lisinopril as the classical ACE inhibitor don’t inhibit ACE-2 activity. ACE-2 may play an important role in regulating the heart function.
CAS Number
9000-83-3
NCBI Gene ID
59272
Swiss Prot
Q9BYF1
Accession Number
Q9BYF1
Tag
C-6 His tag
Type
Recombinant Proteins
Source
Human Cells
Field of Research
Infectious Disease, Innate Immunity, Obesity, Other
Buffer
Supplied as a 0.2 um filtered solution of 20mMTris,300mMNacl,1mMZncl2,10%Glycerol, PH7.4 .
Shipping Conditions
Dry Ice
Calculated Molecular Weight
84.63 kD
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
Angiotensin I converting enzyme 2
NCBI Organism
Homo sapiens
Other Product Names
Angiotensin-Converting Enzyme 2, ACE-Related Carboxypeptidase, Angiotensin-Converting Enzyme Homolog, ACEH, Metalloprotease MPROT15, ACE2
Species
Human
Physical Properties
Liquid
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