ACE-2 Recombinant Protein
Product Specifications
Background
Angiotensin-Converting Enzyme 2 (ACE-2) is an integral membrane protein and a zinc metalloprotease of the ACE family which includes somatic and germinal ACE. ACE-2 cleaves angiotensins I and II as a carboxypeptidase and converts angiotensin I to angiotensin 1-9, and angiotensin II to angiotensin 1-7. ACE-2 is also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. ACE-2 can be highly expressed in testis, kidney, heart, colon, small intestine and ovary at moderate levels. ACE2 is not inhibited by the classical ACE inhibitors, captopril and lisinopril and may play an important role in regulating the heart function.
CAS Number
9000-83-3
NCBI Gene ID
59272
Accession Number
Q9BYF1
Tag
His Tag
Type
Recombinant Proteins
Source
HEK293 cells
Field of Research
Infectious Disease
Concentration
Batch dependent
Purity
>95% as determined by reducing SDS-PAGE.
Buffer
20mM Tris, 300mM NaCl, 1mM ZnCl2, 10% Glycerol, pH 7.4.
Shipping Conditions
Blue Ice
Storage Conditions
Store in working aliquots at -20˚ C. Avoid freeze/thaw cycles.
Calculated Molecular Weight
Mol Mass: 84.63kD; AP Mol Mass: 103kD
NCBI Official Name
Angiotensin-converting enzyme 2
NCBI Organism
Homo sapiens
Other Product Names
Angiotensin-Converting Enzyme 2, ACE-Related Carboxypeptidase, Angiotensin-Converting Enzyme Homolog, ACEH, Metalloprotease MPROT15, ACE2
Species
Human
Physical Properties
Liquid
Frequently Asked Questions
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