AMIGO2 Recombinant Protein
Product Specifications
Background
Amphoterin-Induced Protein 2 (AMIGO2) is a single-pass type I membrane protein which belongs to the AMIGO family of immunoglobulin superfamily. Mature AMIGO2 contains an Ig-like C2-type (immunoglobulin-like) domain, 6 LRR (leucine-rich) repeats, a LRRCT domain, as well as a LRRNT domain. AMIGO2 is mainly expressed in in breast, ovary, cervix, and uterus, although lower in lung, colon, and rectum. AMIGO2 required for depolarization-dependent survival of cultured cerebellar granule neurons. AMIGO2 may mediate homophilic as well as heterophilic cell-cell interaction with AMIGO1 or AMIGO3. AMIGO2 may contribute to signal transduction through its intracellular domain, and may be required for tumorigenesis of a subset of gastric adenocarcinomas.
NCBI Gene ID
347902
Swiss Prot
Q86SJ2
Accession Number
Q86SJ2
Tag
C-6 His tag
Type
Recombinant Proteins
Source
Human Cells
Buffer
Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH 7.2. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.
Shipping Conditions
Room Temp
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=91-504
Calculated Molecular Weight
41.34 kD
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
Adhesion molecule with Ig-like domain 2
NCBI Organism
Homo sapiens
Other Product Names
Amphoterin-Induced Protein 2, AMIGO-2, Alivin-1, Differentially Expressed in Gastric Adenocarcinomas, DEGA, AMIGO2, ALI1
Species
Human
Protein ID
530400175
Physical Properties
Lyophilized
CAS Number
9000-83-3
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