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Alpha-synuclein Recombinant Protein

Product Specifications

Background

Alpha-Synuclein (SNCA) is a member of the Synuclein family. SNCA is expressed principally in brain but also expressed in low concentrations in all tissues except liver. SNCA interacts with UCHL1, Phospholipase D and histones. SNCA can include beta- and gamma-synuclein. In addition, SNCA is an important regulatory component of vesicular transport in neuronal cells. It has been suggested that SNCA is related to the pathogenesis of Parkinson's Disease and neurodegenerative disorders. Defects in SNCA will lead to Dementia Lewy Body (DLB) .

CAS Number

9000-83-3

NCBI Gene ID

20617

Swiss Prot

O55042

Accession Number

O55042

Tag

Tag Free

Type

Recombinant Proteins

Source

E. coli

Field of Research

Neuroscience

Buffer

Lyophilized from a 0.2 um filtered solution of PBS, pH7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.

Shipping Conditions

Room Temp

Calculated Molecular Weight

14.5 kD

Applications Notes

This recombinant protein can be used for biological assays. For research use only.

NCBI Official Name

Synuclein, alpha

NCBI Organism

Mus musculus

Other Product Names

Alpha-synuclein, Non-A beta component of AD amyloid, Non-A4 component of amyloid precursor, NACP, Snca

Species

Mouse

Protein ID

119632232

Physical Properties

Lyophilized

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