Fetuin A Recombinant Protein
Product Specifications
Background
Alpha-2-HS Glycoprotein (AHSG) is a glycoprotein that is composed of two subunits, the A and B chains, belongs to the Cystatin family of proteases inhibitors. It is highly expressed in embryonic cells and adult hepatocytes, and is expressed to a lesser extent in monocytes/macrophages. AHSG is an important circulating inhibitor of calcification in vivo, and is downregulated during the acute-phase response. It is involved in several functions, such as endocytosis, brain development and the formation of bone tissue. In addition, AHSG may influence the resolution of inflammation by modulating the phagocytosis of apoptotic cells by macrophages. ASHG blocks TGF-beta-dependent signaling in osteoblastic cells.
NCBI Gene ID
197
Swiss Prot
P02765
Accession Number
P02765
Tag
C-6 His tag
Type
Recombinant Proteins
Source
Human Cells
Field of Research
Cancer, Cell Cycle, Immunology, Neuroscience, Obesity, Signal Transduction
Buffer
Lyophilized from a 0.2 um filtered solution of 20mM TrisHCl, 150mM NaCl, pH 7.5. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.
Shipping Conditions
Room Temp
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=91-381
Calculated Molecular Weight
38.36 kD
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
Alpha-2-HS-glycoprotein
NCBI Organism
Homo sapiens
Other Product Names
Alpha-2-HS-Glycoprotein, Alpha-2-Z-Globulin, Ba-Alpha-2-Glycoprotein, Fetuin-A, AHSG, FETUA
Species
Human
Physical Properties
Lyophilized
CAS Number
9000-83-3
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