CRYAB Recombinant Protein

Product Specifications

Background

Alpha Crystallin B Chain (CRYAB) is a cytoplasmic protein that belongs to the small heat shock protein (HSP20) family. Alpha crystallins are composed of two gene products: alpha-A and alpha-B, for acidic and basic, respectively. Alpha crystallins can be induced by heat shock and are members of the small heat shock protein (sHSP also known as the HSP20) family. Alpha crystallins acts as molecular chaperones and hold them in in large soluble aggregates. CRYAB is expressed widely in many tissues and organs. It may contribute to the transparency and refractive index of the lens. The deficiency of CRYAB is the cause of myopathy myofibrillar type 2 (MFM2) and cataract posterior polar type 2 (CTPP2) .

CAS Number

9000-83-3

NCBI Gene ID

1410

Swiss Prot

P02511

Accession Number

P02511

Tag

C-6 His tag

Type

Recombinant Proteins

Source

E. coli

Field of Research

Cancer, Neuroscience, Obesity, Signal Transduction, Other

Buffer

Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH 7.2. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.

Shipping Conditions

Room Temp

Calculated Molecular Weight

21.22 kD

Applications Notes

This recombinant protein can be used for biological assays. For research use only.

NCBI Official Name

Crystallin alpha B

NCBI Organism

Homo sapiens

Other Product Names

Alpha-Crystallin B Chain, Alpha (B) -Crystallin, Heat Shock Protein Beta-5, HspB5, Renal Carcinoma Antigen NY-REN-27, Rosenthal Fiber Component, CRYAB, CRYA2