PFKFB1 Recombinant Protein
Product Specifications
Background
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 is an enzyme that in humans is encoded by the PFKFB1 gene. The enzyme forms a homodimer that catalyzes both the synthesis and degradation of fructose-2,6-biphosphate using independent catalytic domains. It belongs to the phosphoglycerate mutase family. Fructose-2,6-biphosphate is an activator of the glycolysis pathway and an inhibitor of the gluconeogenesis pathway. Consequently, regulating fructose-2,6-biphosphate levels through the activity of this enzyme is thought to regulate glucose homeostasis.
NCBI Gene ID
5207
Swiss Prot
P16118
Accession Number
P16118
Tag
C-6 His tag
Type
Recombinant Proteins
Source
Human Cells
Field of Research
Cancer, Neuroscience, Obesity, Signal Transduction
Buffer
Supplied as a 0.2 um filtered solution of 20mM PB,150mM NaCl, pH7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml.
Shipping Conditions
Dry Ice
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=92-350
Calculated Molecular Weight
55.6 kD
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
NCBI Organism
Homo sapiens
Other Product Names
6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase 1, 6PF-2-K/Fru-2, 6-P2ase liver isozyme, Fructose-2, 6-bisphosphatase, PFKFB1, F6PK, PFRX, PFK, FBPase 1
Species
Human
Physical Properties
Liquid
CAS Number
9000-83-3
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