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ERK2-IN-4

ERK2-IN-4 (Compound 6o) is an effective and selective ERK2 inhibitor with a Ki of 0.006 μM. ERK2-IN-4 inhibits the ERK signaling pathway and can be used in cancer research[1].

Product Specifications

CAS Number

933786-58-4

UNSPSC

12352005

Target

ERK

Type

Reference compound

Related Pathways

MAPK/ERK Pathway; Stem Cell/Wnt

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/erk2-in-4.html

Purity

99.9

Solubility

10 mM in DMSO

Smiles

OCC(C1=CC=C(C(Cl)=C1)F)NC(C2=CC(C(NN=C3)=C3C4=CC(Cl)=CC=C4)=CN2)=O

Molecular Formula

C22H17Cl2FN4O2

Molecular Weight

459.30

References & Citations

[1]Aronov, Alex M et al. “Flipped out: structure-guided design of selective pyrazolylpyrrole ERK inhibitors.” Journal of medicinal chemistry vol. 50,6 (2007) : 1280-7.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

ERK2

Available Sizes

Frequently Asked Questions

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