ERK2-IN-4
ERK2-IN-4 (Compound 6o) is an effective and selective ERK2 inhibitor with a Ki of 0.006 μM. ERK2-IN-4 inhibits the ERK signaling pathway and can be used in cancer research[1].
Product Specifications
CAS Number
933786-58-4
UNSPSC
12352005
Target
ERK
Type
Reference compound
Related Pathways
MAPK/ERK Pathway; Stem Cell/Wnt
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/erk2-in-4.html
Purity
99.9
Solubility
10 mM in DMSO
Smiles
OCC(C1=CC=C(C(Cl)=C1)F)NC(C2=CC(C(NN=C3)=C3C4=CC(Cl)=CC=C4)=CN2)=O
Molecular Formula
C22H17Cl2FN4O2
Molecular Weight
459.30
References & Citations
[1]Aronov, Alex M et al. “Flipped out: structure-guided design of selective pyrazolylpyrrole ERK inhibitors.” Journal of medicinal chemistry vol. 50,6 (2007) : 1280-7.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
ERK2
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
