Human BMPR-1A / ALK-3 Protein, Fc Tag
Human BMPR-1A, Fc Tag (AL3-H5259) is expressed from human 293 cells (HEK293) . It contains AA Gln 24 - Arg 152 (Accession # P36894-1) .
Product Specifications
Background
The bone morphogenetic protein receptor, type IA is also known as BMPR1A or ALK3 is a protein which in humans is encoded by the BMPR1A gene. BMPR1A has also been designated as CD292 (cluster of differentiation 290) . The bone morphogenetic protein (BMP) receptors are a family of transmembrane serine/threonine kinases that include the type I receptors BMPR1A (this protein) and BMPR1B and the type II receptor BMPR2. These receptors are also closely related to the activin receptors, ACVR1 and ACVR2. Alk3-mediated BMP signaling in AV endocardial/mesenchymal cells plays a central role during cushion morphogenesis.
Specifications
This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 40.3 kDa. The protein migrates as 56 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Accession Number
P36894-1
Expression Region
Gln 24 - Arg 152
Host
HEK293
Target
BMPR-1A
Conjugation
Unconjugated
Tag
C-Fc
Source
Human
Stability
● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Endotoxin
1.0 EU per μg
Purity
98%
Format
Powder
Buffer
50 mM Tris, 100 mM Glycine, pH7.5
Additives
Trehalose
Molecular Weight
40.3 kDa
Shipping Conditions
RT
Storage Conditions
-20°C
Package Size
200ug*1
Product Datasheet
Https://www.acrobiosystems.com/static/main/products/pdf/ds/AL3-H5259.pdf
Species
Human
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