7-Deaza-2′-deoxyguanosine 5′-triphosphate

7-Deaza-2′-deoxyguanosine 5′-triphosphate (7-Deaza-2'-dGTP), a nucleotide analogue, is a telomerase inhibitor (IC50: 11 μM)[1].

Telomerase

Reference compound

Cell Cycle/DNA Damage

Cancer-programmed cell death

Cancer

https://www.medchemexpress.com/7-deaza-2-deoxyguanosine-5-triphosphate.html

10 mM in DMSO

O[C@H]1C[C@H](N2C(N=C(N)NC3=O)=C3C=C2)O[C@@H]1COP(OP(OP(O)(O)=O)(O)=O)(O)=O

506.19

[1]Fletcher TM, et al. Human telomerase inhibition by 7-deaza-2'-deoxypurine nucleoside triphosphates. Biochemistry. 1996 Dec 10;35(49):15611-7.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-W250161/7-Deaza-2-deoxyguanosine-5-triphosphate-DataSheet-MedChemExpress.pdf

http://file.medchemexpress.com/batch_PDF/HY-W250161/

No Development Reported

101515-08-6