7-Deaza-2′-deoxyguanosine 5′-triphosphate
7-Deaza-2′-deoxyguanosine 5′-triphosphate (7-Deaza-2'-dGTP), a nucleotide analogue, is a telomerase inhibitor (IC50: 11 μM) [1].
Product Specifications
CAS Number
[101515-08-6]
Product Name Alternative
7-Deaza-2'-dGTP
UNSPSC
12352005
Hazard Statement
H371
Target
Telomerase
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/7-deaza-2-deoxyguanosine-5-triphosphate.html
Solubility
10 mM in DMSO
Smiles
O[C@H]1C[C@H](N2C(N=C(N)NC3=O)=C3C=C2)O[C@@H]1COP(OP(OP(O)(O)=O)(O)=O)(O)=O
Molecular Formula
C11H17N4O13P3
Molecular Weight
506.19
Precautions
P260-P264-P270-P405-P501
References & Citations
[1]Fletcher TM, et al. Human telomerase inhibition by 7-deaza-2'-deoxypurine nucleoside triphosphates. Biochemistry. 1996 Dec 10;35 (49) :15611-7.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
More Discoveries
Explore Other Products
Browse additional items from our catalog
TL509850V 500 µL Each
Nob1 Mouse shRNA Lentiviral Particle (Locus ID 67619)
Sign In for Pricing
View Details 
