7-Deaza-2′-deoxyguanosine 5′-triphosphate

7-Deaza-2′-deoxyguanosine 5′-triphosphate (7-Deaza-2'-dGTP), a nucleotide analogue, is a telomerase inhibitor (IC50: 11 μM) [1].

Product Specifications

CAS Number

[101515-08-6]

Product Name Alternative

7-Deaza-2'-dGTP

UNSPSC

12352005

Hazard Statement

H371

Target

Telomerase

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/7-deaza-2-deoxyguanosine-5-triphosphate.html

Solubility

10 mM in DMSO

Smiles

O[C@H]1C[C@H](N2C(N=C(N)NC3=O)=C3C=C2)O[C@@H]1COP(OP(OP(O)(O)=O)(O)=O)(O)=O

Molecular Formula

C11H17N4O13P3

Molecular Weight

506.19

Precautions

P260-P264-P270-P405-P501

References & Citations

[1]Fletcher TM, et al. Human telomerase inhibition by 7-deaza-2'-deoxypurine nucleoside triphosphates. Biochemistry. 1996 Dec 10;35 (49) :15611-7.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

NBP2-74241V 0.1 mL

Mouse Monoclonal SMURF2 Antibody (OTI3E4) [DyLight 405]

Ask

View Details

NBP2-57502PEP 100 µL

CYFIP2 Recombinant Protein Antigen

Ask

View Details

168640-ML490 100 µL

ACTH (Adrenocorticotropin, alpha or beta or gamma Melanocyte Stimulating Hormone (MSH) or Melanotropin, beta-Endorphin, beta or gamma Lipotropin (LPH), CLIP, Met Enkephalin, POC, POMC) (MaxLight 490) discontinued

Ask

View Details

NBP3-12741UV 100 µL

Rabbit Monoclonal Influenza A nucleoprotein Antibody (010) [DyLight 350]

Ask

View Details

169522 20 µg

Bone Morphogenetic Protein 7 (BMP7, BMP-7) (Not for Export EU)

Ask

View Details