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Anti-Mouse IL-10R/CD210 Antibody (1B1.3A)

Anti-Mouse IL-10R/CD210 Antibody (1B1.3A) is a rat-derived IgG1 κ type antibody inhibitor, targeting to mouse IL-10R/CD210. Anti-Mouse IL-10R/CD210 Antibody (1B1.3A) blocks IL-10R signaling. Anti-Mouse IL-10R/CD210 Antibody (1B1.3A) can be used for the researches of cancer, infection and metabolic disease, such as diabetes and malaria[1][2][3][4][5].

Product Specifications

CAS Number

9007-83-4

UNSPSC

12352203

Target

Fungal; Interleukin Related; Parasite

Type

Inhibitory Antibodies

Related Pathways

Anti-infection; Immunology/Inflammation

Field of Research

Infection; Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/anti-mouse-il-10r-cd210-antibody-1b1-3a.html

Purity

95.00

Solubility

10 mM in DMSO

Smiles

[Anti-MouseIL-10R/CD210Antibody(1B1.3A)]

Molecular Weight

(150 kDa)

References & Citations

[1]Murdock BJ, et al. Early or late IL-10 blockade enhances Th1 and Th17 effector responses and promotes fungal clearance in mice with cryptococcal lung infection. J Immunol. 2014 Oct 15;193 (8) :4107-16.|[2]Claser C, et al. Host Resistance to Plasmodium-Induced Acute Immune Pathology Is Regulated by Interleukin-10 Receptor Signaling. Infect Immun. 2017 May 23;85 (6) :e00941-16. |[3]harma S, et al. A pathogenic role for IL-10 signalling in capillary stalling and cognitive impairment in type 1 diabetes. Nat Metab. 2024 Nov;6 (11) :2082-2099.|[4]Thompson EA, et al. Monocytes Acquire the Ability to Prime Tissue-Resident T Cells via IL-10-Mediated TGF-β Release. Cell Rep. 2019 Jul 30;28 (5) :1127-1135.e4.|[5]Stirm K, et al. Tumor cell-derived IL-10 promotes cell-autonomous growth and immune escape in diffuse large B-cell lymphoma. Oncoimmunology. 2021 Nov 22;10 (1) :2003533.

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4°C for 2 years, do not freeze

Scientific Category

Inhibitory Antibodies

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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