Oncrasin-60

Oncrasin-60 (NSC-741909) is a compound with antitumor activity that is active against multiple cancer cell lines in vitro and can induce tumor regression in vivo, with its mechanism involving JNK activation and STAT3 inhibition.

Product Specifications

CAS Number

[92407-91-5]

Product Name Alternative

NSC-741909

UNSPSC

12352005

Target

Apoptosis; JNK

Type

Reference compound

Related Pathways

Apoptosis; MAPK/ERK Pathway

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/oncrasin-60.html

Purity

99.79

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

OCC1=CN(C2=C1C=CC=C2)CC3=CC=C(C=C3)Cl

Molecular Formula

C16H14ClNO

Molecular Weight

271.74

References & Citations

[1]Antitumor activity of a novel oncrasin analogue is mediated by JNK activation and STAT3 inhibition

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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