Mulberrofuran H

Mulberrofuran H is a 2-arylbenzofuran derivative from the cultivated mulberry tree (Morus lhou (ser.) Koidz.) . Mulberrofuran H demonstrates potent inhibition against substrates L-tyrosine (IC50=4.45 µM) and L-DOPA (IC50=19.70 µM) . Mulberrofuran H also shows potent anti-inflammatory and antioxidative activities[1][2][3].

Product Specifications

CAS Number

[89199-99-5]

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Dopamine Receptor

Type

Natural Products

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/mulberrofuran-h.html

Solubility

10 mM in DMSO

Smiles

C[C@@]12CC(CC(C3=C(C=C(C4=CC5=C(C=C(O)C=C5)O4)C=C3O)O)=C2)C6=CC=C(O)C=C6O1

Molecular Formula

C27H22O6

Molecular Weight

442.46

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Fukai T, et al. Structure of mulberrofuran H, a novel 2-arylbenzofuran derivative from the cultivated mulberry tree (Morus lhou (ser.) Koidz.) [J]. Chemical and pharmaceutical bulletin, 1984, 32 (2) : 808-811. |[2]Kang J, et al. Five new diels-alder type adducts from the stem and root bark of Morus mongolica. Planta Med. 2006 Jan;72 (1) :52-9. |[3]Paudel P, et al. Antioxidant and anti-browning property of 2-arylbenzofuran derivatives from Morus alba Linn root bark. Food Chem. 2020 Mar 30;309:125739.