Turosteride

Turosteride is a selective 5 alpha-reductase inhibitor, with IC50 values of 55 and 53 nM for human and rat prostatic 5 alpha-reductases, respectively. Turosteride can reduce the prostate and seminal vesicle weights[1].

Product Specifications

CAS Number

[137099-09-3]

Product Name Alternative

FCE 26073

UNSPSC

12352005

Target

5 alpha Reductase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/turosteride.html

Solubility

10 mM in DMSO

Smiles

C[C@@]12[C@](CC[C@@H]2C(N(C(C)C)C(NC(C)C)=O)=O)([H])[C@@]3([H])[C@]([C@@]4([C@@](N(C(CC4)=O)C)([H])CC3)C)([H])CC1

Molecular Formula

C27H45N3O3

Molecular Weight

459.66

References & Citations

[1]Di Salle E, et al. Endocrine properties of the testosterone 5 alpha-reductase inhibitor turosteride (FCE 26073) . J Steroid Biochem Mol Biol. 1994 Feb;48 (2-3) :241-8.