IGRP (206-214)
IGRP (206-214) is a biological active peptide. IGRP (206-214) corresponds to residues 206-214 of murine islet-specific glucose-6-phosphatase catalytic subunit-related protein (IGRP) . IGRP (206-214) is T cells specific for proinsulin and IGRP induces diabetes in non-obese diabetic (NOD) mice[1].
Product Specifications
CAS Number
849069-99-4
UNSPSC
12352209
Target
IFNAR
Type
Peptides
Related Pathways
Immunology/Inflammation
Field of Research
Metabolic Disease; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/igrp-206-214.html
Purity
96.40
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
OC(C=C1)=CC=C1C[C@H](NC([C@@H](N)C(C)C)=O)C(N[C@@H](CC(C)C)C(N[C@@H](CCCCN)C(N[C@@H]([C@H](O)C)C(N[C@@H](CC(N)=O)C(N[C@@H](C(C)C)C(N[C@H](C(N[C@H](C(O)=O)CC(C)C)=O)CC2=CC=CC=C2)=O)=O)=O)=O)=O)=O
Molecular Formula
C54H85N11O13
Molecular Weight
1096.32
References & Citations
[1]Krishnamurthy B, et al., Autoimmunity to both proinsulin and IGRP is required for diabetes in nonobese diabetic 8.3 TCR transgenic mice. J Immunol. 2008 Apr 1;180 (7) :4458-64.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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