N-Formyl-L-histidine
N-Formyl-L-histidine shows binding affinity to histidyl-tRNA synthetase with a Ki value of 4.6 μM. N-Formyl-L-histidine shows a competitive inhibition against L-histidine ammonia-lyase, inhibits urocanic acid formation from L-histidine with a Ki value of 4.26 mM[1][2].
Product Specifications
CAS Number
15191-21-6
Product Name Alternative
Formyl-L-histidine
UNSPSC
12352209
Hazard Statement
H302-H315-H319-H335
Target
Aminoacyl-tRNA Synthetase
Type
Peptides
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/n-formyl-l-histidine.html
Solubility
10 mM in DMSO
Smiles
O=C(O)[C@@H](NC=O)CC1=CN=CN1
Molecular Formula
C7H9N3O3
Molecular Weight
183.16
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
References & Citations
[1]Lepore GC, et al. Histidyl-tRNA synthetase from Salmonella typhimurium: specificity in the binding of histidine analogues. Eur J Biochem. 1975 Aug 15;56 (2) :369-74.|[2]Shibatani T, et al. Crystalline L-histidine ammonia-lyase of Achromobacter liquidum. Crystallization and enzymic properties. Eur J Biochem. 1975 Jun 16;55 (1) :263-9.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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