(+) -Nipecotic acid
(+) -Nipecotic acid ((+) -β-Homoproline) is a GABA transport inhibitor with potential antidepressant and anxiolytic activities. (+) -Nipecotic acid can increase the concentration of GABA in the synaptic cleft, thereby enhancing inhibitory neurotransmission. The research on (+) -Nipecotic acid provides a possible direction for the development of new inhibitory compounds for psychiatric diseases[1].
Product Specifications
CAS Number
[59045-82-8]
Product Name Alternative
(+) -β-Homoproline; (+) -Hexahydronicotinic acid; (+) -3-Carboxypiperidine
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
GABA Receptor
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/plus-nipecotic-acid.html
Purity
98.0
Smiles
O=C([C@]1([H])CNCCC1)O
Molecular Formula
C6H11NO2
Molecular Weight
129.16
Precautions
H315, H319, H335
References & Citations
[1]Inhibition of the uptake of GABA and related amino acids in rat brain slices by the optical isomers of nipecotic acid
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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