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(+) -Nipecotic acid

(+) -Nipecotic acid ((+) -β-Homoproline) is a GABA transport inhibitor with potential antidepressant and anxiolytic activities. (+) -Nipecotic acid can increase the concentration of GABA in the synaptic cleft, thereby enhancing inhibitory neurotransmission. The research on (+) -Nipecotic acid provides a possible direction for the development of new inhibitory compounds for psychiatric diseases[1].

Product Specifications

CAS Number

59045-82-8

Product Name Alternative

(+) -β-Homoproline; (+) -Hexahydronicotinic acid; (+) -3-Carboxypiperidine

UNSPSC

12352005

Hazard Statement

H315, H319, H335

Target

GABA Receptor

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/plus-nipecotic-acid.html

Purity

98.0

Smiles

O=C([C@]1([H])CNCCC1)O

Molecular Formula

C6H11NO2

Molecular Weight

129.16

Precautions

H315, H319, H335

References & Citations

[1]Inhibition of the uptake of GABA and related amino acids in rat brain slices by the optical isomers of nipecotic acid

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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