Diosgenin glucoside

Diosgenin glucoside, a saponin compound extracted from Trillium tschonoskii, provides neuroprotection by regulating microglial M1 polarization. Diosgenin glucoside protects against spinal cord injury by regulating autophagy and alleviating apoptosis [1][2].

Product Specifications

CAS Number

[14144-06-0]

UNSPSC

12352005

Target

Apoptosis; Autophagy

Type

Natural Products

Related Pathways

Apoptosis; Autophagy

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/diosgenin-glucoside.html

Purity

99.94

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

C[C@@]12[C@]([C@@H]3C)([H])[C@](O[C@]34CC[C@@H](C)CO4)([H])C[C@@]1([H])[C@@](CC=C5[C@@]6(CC[C@H](O[C@]([C@@H]([C@@H](O)[C@@H]7O)O)([H])O[C@@H]7CO)C5)C)([H])[C@]6([H])CC2

Molecular Formula

C33H52O8

Molecular Weight

576.76

References & Citations

[1]Int Immunopharmacol. 2017 Sep;50:22-29. doi: 10.1016/j.intimp.2017.06.008. Epub 2017 Jun 14.|[2]Chen XB, et al. Diosgenin Glucoside Protects against Spinal Cord Injury by Regulating Autophagy and Alleviating Apoptosis. Int J Mol Sci. 2018 Aug 2;19 (8) . pii: E2274.