Oxotremorine

Oxotremorine is an agonist for mAChR, that activates M1 and M3 acetylcholine receptors. Oxotremorine exhibits nicotine-like effects in drug discrimination experiments in macaques[1].

Product Specifications

CAS Number

[70-22-4]

UNSPSC

12352005

Target

MAChR

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/oxotremorine.html

Smiles

O=C1N(CCC1)CC#CCN2CCCC2

Molecular Formula

C12H18N2O

Molecular Weight

206.28

References & Citations

[1]Moerke MJ, et al., Nicotine-like discriminative stimulus effects of acetylcholinesterase inhibitors and a muscarinic receptor agonist in Rhesus monkeys. Drug Dev Ind Pharm. 2019 May;45 (5) :861-867.