4-Thiothymidine
4-Thiothymidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Product Specifications
CAS Number
[7236-57-9]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Nucleoside Antimetabolite/Analog
Type
Oligonucleotides
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/4-thiothymidine.html
Purity
99.69
Solubility
DMSO : 116.67 mg/mL (ultrasonic)
Smiles
OC[C@@H]1[C@@H](O)C[C@H](N2C(NC(C(C)=C2)=S)=O)O1
Molecular Formula
C10H14N2O4S
Molecular Weight
258.29
Precautions
H302, H315, H319, H335
References & Citations
[1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18 (23) :3373-88.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Oligonucleotides
Clinical Information
No Development Reported
Available Sizes
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