Anti-Mouse IL-12 p40 Antibody (C17.8)
Anti-Mouse IL-12 p40 Antibody (C17.8) is a rat-derived anti-mouse IL-12 p40 IgG2a κ type antibody inhibitor. Anti-Mouse IL-12 p40 Antibody (C17.8) binds p40 subunit of IL-12. Anti-Mouse IL-12 p40 Antibody (C17.8) can be used for the researches of inflammation, immunology and metabolic disease, such as diabetes and arthritis[1][2][3].
Product Specifications
CAS Number
9007-83-4
UNSPSC
12352203
Target
Interleukin Related
Type
Inhibitory Antibodies
Related Pathways
Immunology/Inflammation
Field of Research
Metabolic Disease; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/anti-mouse-il-12-p40-antibody-c17-8.html
Purity
95.00
Solubility
10 mM in DMSO
Smiles
[Anti-MouseIL-12p40Antibody(C17.8)]
Molecular Weight
(150 kDa)
References & Citations
[1]Fujihira K, et al. Suppression and acceleration of autoimmune diabetes by neutralization of endogenous interleukin-12 in NOD mice. Diabetes. 2000 Dec;49 (12) :1998-2006.|[2]Joosten LA, et al. Blockade of endogenous interleukin 12 results in suppression of murine streptococcal cell wall arthritis by enhancement of interleukin 10 and interleukin 1Ra. Ann Rheum Dis. 2000 Mar;59 (3) :196-205.|[3]Gaignage M, et al. Novel antibodies that selectively block mouse IL-12 enable the re-evaluation of the role of IL-12 in immune protection and pathology. Eur J Immunol. 2021 Jun;51 (6) :1482-1493.
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4°C for 2 years, do not freeze
Scientific Category
Inhibitory Antibodies
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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